There are going to be times when we can't wait for somebody. Now, you're either on the bus or off the bus. If you're on the bus, and you get left behind, then you'll find it again. If you're off the bus in the first place — then it won't make a damn.

The answer is never the answer. What's really interesting is the mystery. If you seek the mystery instead of the answer, you'll always be seeking. I've never seen anybody really find the answer, but they think they have. So they stop thinking. But the job is to seek mystery, evoke mystery, plant a garden in which strange plants grow and mysteries bloom. The need for mystery is greater than the need for an answer.

I believe that with the advent of acid, we discovered a new way to think, and it has to do with piecing together new thoughts in your mind. Why is it that people think it's so evil ? What is it about it that scares people so deeply, even the guy that invented it, what is it ? Because they're afraid that there's more to reality than they have confronted. That there are doors that they're afraid to go in, and they don't want us to go in there either, because if we go in we might learn something that they don't know. And that makes us a little out of their control.

There’s no doubt in my mind that McMurphy’s won, but I’m not sure what.

Anti-drug fanatics and cops are the criminals - it's like McCarthyism. They need someone to dislike to distract the public from the really important problems.

Because he knows you have to laugh at the things that hurt you just to keep yourself in balance, just to keep the world from running you plumb crazy. He knows there's a painful side; he knows my thumb smarts and his girlfriend has a bruised breast and the doctor is losing his glasses, but he won't let the pain blot out the humor no more'n he'll let the humor blot out the pain.

The trouble with super heroes is what to do between phone booths.