In some ways, the most rewarding thing I've done were the two times that I did the Oscars, particularly the first time because it was really like the ultimate "Let's put on a show," with every great movie star in the world available.

In my world, the hero always defeats the villain, the boy always gets the girl, and cancer is no more.

Most movies don't have the ability to find an audience. So the movie plays out very quickly in a lot of theaters to get the biggest gross. So that demands that we make things that are hits before they open. So they have to have the elements, they have to be franchises.

For me as a filmmaker, I do the projects I'm really excited about.

I think being a producer makes you a problem solver, so you kind of go, "Well there's a problem. What do we do? How do we solve it?"

Cancer is everybody's cause.

I think it's hard for women to be directors, particularly in the feature world because, biologically, your peak career-making years are also your peak baby-making years, and that's just the truth. And those are choices women have to make.