When I think of cancer prevention, I think of cancer vaccines, but I think more broadly of all that we can do to prevent cancer. And part of that is coming up with a vaccine that will work like the vaccines we have for hepatitis B or flu or polio.
Laurie GlimcherIf one has a routine colonoscopy at the age of 50 and then colonoscopies thereafter as the physician recommends, you could largely prevent colon cancer, you could detect it in its very earliest stages and cure it.
Laurie GlimcherPrecision medicine is diving into the DNA with a knowledge that everybody's tumor has a unique genetic profile and you want to be able to identify that specific piece of DNA that has become mutated and that is driving cancer growth.
Laurie GlimcherCancer vaccines are in the future. And they could be very effective. Checkpoint blockade, which is acting your immune system to recognize those cancer cells and kill them is another very promising approach and there have been some checkpoint blockade drugs out in the market now that will release the brake on T lymphocytes, the T lymphocyte is your major killer of tumor cells.
Laurie GlimcherThe decrease in incidents of death from cancer is largely attributable to new medicines or therapeutics. Perhaps a third is attributable to changing our environment, and that includes of course smoking which I believe accounted for probably 20 percent of deaths from, certainly from lung cancer, more than that from lung cancer, but from cancer overall.
Laurie Glimcher