Cancer vaccines are in the future. And they could be very effective. Checkpoint blockade, which is acting your immune system to recognize those cancer cells and kill them is another very promising approach and there have been some checkpoint blockade drugs out in the market now that will release the brake on T lymphocytes, the T lymphocyte is your major killer of tumor cells.
Laurie GlimcherProbably all of us have random rogue cancer cells floating around in our bodies but by and large, in the majority of cases, our immune system circulates and acts as a surveillance mechanism and kills off those few tumor cells.
Laurie GlimcherThere are clearly environmental factors that can decrease the incidence and death from cancer. I would still say though that the majority of cancers cannot be prevented at this point, but they can be treated and they can be treated two major ways.
Laurie GlimcherI think that the marriage of academic medical centers and academicians with the private sector is a very, is a marriage made in heaven because it's the best way to get basic discoveries from the laboratory into new therapeutics for our patients.
Laurie GlimcherPrecision medicine is one way to attack cancer and it's proven to be very effective but, remember that like HIV/AIDS, you're going to need combination therapies.
Laurie GlimcherWhen you think of the costs of cancer care, one can imagine that drugs like checkpoint blockers or transfer of these T lymphocytes are actually cost-saving, just as treatments for hepatitis C, while expensive, overall save money by preventing hepatitis and hep - hepatocarcinoma in patients.
Laurie GlimcherThe decrease in incidents of death from cancer is largely attributable to new medicines or therapeutics. Perhaps a third is attributable to changing our environment, and that includes of course smoking which I believe accounted for probably 20 percent of deaths from, certainly from lung cancer, more than that from lung cancer, but from cancer overall.
Laurie Glimcher