What science is all about is a process. It's like saying, "Well, is it important for people to know that World War II happened?" Well it's part of what makes us who we are. And so, there's basic bits of science we need to know.

We now know that we are more insignificant than we ever imagined. If you get rid of everything we see, the universe is essentially the same. We constitute a 1 percent bit of pollution in a universe . . . we are completely irrelevant.

[The writers of the holy books] did not even know the earth revolves around the sun. Why are we listening?

The one experience that I hope every student has at some point in their lives is to have some belief you profoundly, deeply hold, proved to be wrong because that is the most eye-opening experience you can have, and as a scientist, to me, is the most exciting experience I can ever have.

Discerning the merits of competing claims is where the empirical basis of science should play a role. I cannot stress often enough that what science is all about is not proving things to be true but proving them to be false. What fails the test of empirical reality, as determined by observation and experiment, gets thrown out like yesterday's newspaper.

Science has been effective at furthering our understanding of nature because the scientific ethos is based on three key principles: (1) follow the evidence wherever it leads; (2) if one has a theory, one needs to be willing to try to prove it wrong as much as one tries to prove that it is right; (3) the ultimate arbiter of truth is experiment, not the comfort one derives from one's a priori beliefs, nor the beauty or elegance one ascribes to one's theoretical models.

If we wish to draw philosophical conclusions about our own existence, our significance, and the significance of the universe itself, our conclusions should be based on empirical knowledge. A truly open mind means forcing our imaginations to conform to the evidence of reality, and not vice versa, whether or not we like the implications.