It was obvious-to me at any rate-that the answer was to why an enzyme is able to speed up a chemical reaction by as much as 10 million times. It had to do this by lowering the energy of activation-the energy of forming the activated complex. It could do this by forming strong bonds with the activated complex, but only weak bonds with the reactants or products.
Linus PaulingThe McCarthy period came along...and many of the other scientists who had been working on these same lines gave up. Probably saying "Why should I sacrifice myself? I am a scientist, I am supposed to be working on scientific things, so I don't need to put myself at risk by talking about these possibilities." And I have said that perhaps I'm just stubborn... I have said "I don't like anybody to tell me what to do or to think, except Mrs. Pauling."
Linus PaulingI hear from patients who say their doctor said, 'If you want to take Vitamin C, go ahead and do it. It won't harm you, and it may do you some good.' More and more physicians are getting convinced about the value of large doses of Vitamin C.
Linus PaulingScience is the search for the truth--it is not a game in which one tries to beat his opponent, to do harm to others. We need to have the spirit of science in international affairs, to make the conduct of international affairs the effort to find the right solution, the just solution of international problems, and not an effort by each nation to get the better of other nations, to do harm to them when it is possible. I believe in morality, in justice, in humanitarianism.
Linus PaulingYou have to have a lot of ideas. First, if you want to make discoveries, it's a good thing to have good ideas. And second, you have to have a sort of sixth sense-the result of judgment and experience-which ideas are worth following up. I seem to have the first thing, a lot of ideas, and I also seem to have good judgment as to which are the bad ideas that I should just ignore, and the good ones, that I'd better follow up.
Linus Pauling