We may, I believe, anticipate that the chemist of the future who is interested in the structure of proteins, nucleic acids, polysaccharides, and other complex substances with high molecular weight will come to rely upon a new structural chemistry, involving precise geometrical relationships among the atoms in the molecules and the rigorous application of the new structural principles, and that great progress will be made, through this technique, in the attack, by chemical methods, on the problems of biology and medicine.
Linus PaulingAn amino acid residue (other than glycine) has no symmetry elements. The general operation of conversion of one residue of a single chain into a second residue equivalent to the first is accordingly a rotation about an axis accompanied by translation along the axis. Hence the only configurations for a chain compatible with our postulate of equivalence of the residues are helical configurations.
Linus PaulingWhen an old and distinguished person speaks to you, listen to him carefully and with respect โ but do not believe him. Never put your trust into anything but your own intellect. Your elder, no matter whether he has gray hair or has lost his hair, no matter whether he is a Nobel laureate โ may be wrong. The world progresses, year by year, century by century, as the members of the younger generation find out what was wrong among the things that their elders said. So you must always be skeptical โ always think for yourself.
Linus Pauling[Professor Pauling] confesses that he had harboured the feeling that sooner or later he would be the one to get the DNA structure; and although he was pleased with the double-helix, he 'rather wished the idea had been his'.
Linus PaulingThe McCarthy period came along...and many of the other scientists who had been working on these same lines gave up. Probably saying "Why should I sacrifice myself? I am a scientist, I am supposed to be working on scientific things, so I don't need to put myself at risk by talking about these possibilities." And I have said that perhaps I'm just stubborn... I have said "I don't like anybody to tell me what to do or to think, except Mrs. Pauling."
Linus Pauling