Addiction is when you fall in love with a drug instead of a child or a lover and the learning that takes part in that part of the brain is designed by evolution to get us to persist despite negative consequences to do what we need to do - because I don't know anybody who could survive a relationship or parenting if not for the ability to persist despite negative consequences. The problem is when that gets misdirected to a drug and then you can find yourself in some very negative and potentially deadly situations.

A lot of addiction actually ends by age 30 - something like 50 percent of all addictions with the exception of tobacco - and I think a lot of what's going on there is that the self-control areas of the brain are finally developed enough to be able to stop yourself from relapsing or just continuing. There is a maturational aspect to it as well.

There is a safe, nontoxic drug called naloxone that can instantly reverse opioid overdose and prevent most of these deaths. But the drug war interferes with saving overdose victims in two ways: first, because witnesses to overdose fear prosecution, they often don't call for help until it's too late. Second, because the drug war supports the belief that making naloxone available over-the-counter or with opioid prescriptions would encourage drug use, the antidote is available only through harm reduction programs like needle exchanges or in some state programs aimed at drug users.

Incarceration is as useful for addiction as it is for diabetes - i.e., not useful and potentially harmful, particularly for kids.

I think our drug laws need to be made scientifically, as best as possible, recognizing that values will always be part of that.

The thing about our drug laws is that they're not based on science.

We should not be putting kids in cages and hoping that is going to fix their psychological problems of any type.