Living a long life, the conventional wisdom at the time said, depended to a great extent on who we were-that is, our genes. It depended on the decisions we made-on what we chose to eat, and how much we chose to exercise, and how effectively we were treated by the medical system. No one was used to thinking about health in terms of community.

The key to good decision making is not knowledge... It's whether our work fulfills us.

Shortly after the birth control pill was approved for public distribution, one woman wrote to John Rock, its inventor, "You should be afraid to meet your maker." Rock, despite being Catholic replied, "My dear Madam, in my faith, we are taught that the Lord is with us always. When my time comes, there will be no need for introductions."

People at CDC [Centers for Disease Control] who cut their teeth on diseases over the last 10 years have started to think of crime as another disease, and using some of these same concepts. It was something that was in the air in that world, but it was time to bust it out and apply it to any number of different social epidemics.

Sometimes [genius] is just the thing that emerges after twenty years of working at your kitchen table.

The successful are those who have been given opportunities.

When you're an underdog, you're forced to try things you would never otherwise have attempted.