Almost every dot-com idea from 1999 that failed will succeed.

The good news about building a company during times like this is that the companies that do succeed are going to be extremely strong and resilient.

In short, software is eating the world

There is a constant need for new systems and new software.

Working for a big company is, I believe, much risker than it looks.

People are so bad at driving cars that computers don't have to be that good to be much better. Any time you stand in line at the D.M.V. and look around, you're like, 'Oh, my God, I wish all these people were replaced by computer drivers.'

Breakthrough ideas look crazy, nuts. It’s hard to think this way — I see it in other people’s body language, and I can feel it in my own, where I sometimes feel like I don’t even care if it’s going to work, I can’t take more change. O.K., Google, O.K., Twitter—but Airbnb? People staying in each other’s houses without there being a lot of axe murders?