Keep the faith. Whatever that may be. Don't get too depressed yet, because I have a belief in America being very diverse and ornery, and containing a lot of people who are not going to roll over very easily for a totalitarian dictatorship. That is what I think.

Marshall McLuhan is absolutely right, we are always looking in the rear view mirror.

I know that some books and some writers, you can pretty much draw a square around it and say, 'Nobody under 40,' or 'Nobody under 25.' With my books, it always has been, and continues to be, spread right across the board, and I think the operative term is 'reader.'

I did ... learn an important distinction in graduate school: a speculation about who had syphilis when is gossip if it's about your friends, a plot element if it's about a character in a novel, and scholarship if it's about John Keats.

It's a critical fallacy of our times ... that a writer should 'grow,' 'change,' or 'develop.' This fallacy causes us to expect from children or radishes: 'grow,' or there's something wrong with you. But writers are not radishes. If you look at what most writers actually do, it resembles a theme with variations more than it does the popular notion of growth.

When things are really dismal, you can laugh, or you can cave in completely.

Please don't make the mistake of thinking that 'Oryx and Crake' is anti-science. Science is a way of knowing, and a tool. Like all ways of knowing and tools, it can be turned to bad uses. And it can be bought and sold, and it often is. But it is not in itself bad. Like electricity, it's neutral.