Laughter is important, not only because it makes us happy, it also has actual health benefits. And that's because laughter completely engages the body and releases the mind. It connects us to others, and that in itself has a healing effect.

The rejection that we all take and the sadness and the aggravation and the loss of jobs and all of the things that we live through in our lives, without a sense of humor, I don't know how people make it.

Where will I be five years from now? I delight in not knowing. That's one of the greatest things about life its wonderful surprises.

When I look back at those pictures of my mother performing - and listen to her recordings - it makes me sad to think that all of that joy she found in her work came to an end. I wish she hadn't had to make that sacrifice, even if it was for the benefit of my father and siblings and me.

That is the difference between St. Jude's and all other children's hospitals. The other hospitals are not bad at all; they're good hospitals, but they're just working with what they know, and St. Jude's is working with what nobody else knows, because they're doing research.

My mother was a strong-willed and opinionated woman - a Sicilian! - and if she didn't like something, she'd let you know about it. So her undying support of her kids went a long way in proving to us that we were on the right path.

I wish someone would have told me that, just because I'm a girl, I don't have to get married.