Ive always been a champion of kids pursuing their dreams. But sometimes in life, extraordinary circumstances may force us to temporarily put our dreams on hold. The most important thing is to never lose sight of that dream, no matter what punches life may throw in our way.

I find that balancing my life with my work with the kids at St. Jude, working on books, working on my career as an actor and taking time out for my husband and family help to cushion a lot of the blows.

As someone who has spent many years marveling at the brilliant and painstaking work of the doctors, scientists and researchers at St. Jude, I can attest firsthand to the bone-deep commitment these men and women have made in their fight against disease. They are at it around the clock - every hour of the day, every day of the year.

That is the difference between St. Jude's and all other children's hospitals. The other hospitals are not bad at all; they're good hospitals, but they're just working with what they know, and St. Jude's is working with what nobody else knows, because they're doing research.

It's important to think big, but you've got to work small.

I realize now that I was a feminist and the minute I heard the word I certainly knew it meant me, but at that time I don't think we had the label yet. But there's no doubt about it that I was born a feminist.

The rejection that we all take and the sadness and the aggravation and the loss of jobs and all of the things that we live through in our lives, without a sense of humor, I don't know how people make it.