I saw a werewolf drinking a pina colada at Trader Vic's. His hair was perfect.

If you have reached the point where you're certain that person has no conscience, or is in it to win rather than to love you, then the very best thing you can do is to get away. That's a very hard lesson to learn, and, furthermore, it's not always possible.

Being sociopath is not what most people would consider to be winning. Most of us have some kind of positive goal in mind when we think of winning. A sociopath thinks in terms of successfully manipulating someone into doing something that he or she would not have done otherwise. That can be a small thing or a tremendous thing, but the point for the sociopath is to win, to make sure that this person does what they're trying to coerce him or her into doing. It can be as disgusting and as simple as making a child cry. Or it can be as complex as making your wife feel bad about herself.

The physical basis for sociopathy is approximately 50 percent inheritable, which sounds more dramatic than it probably is, because most personality characteristics that psychologists test for and study the genetics of are about 50 percent inheritable. Introversion, extroversion, it turns out that they're about 50 percent inheritable, which means that somehow sociopathy is physical, it's organic.

In Western culture, particularly North America, a lot of rules are descriptors for sociopathy: a general acceptance of lying as long as you win, an attitude of "me first," an attitude that what it looks like is more important than what it is. This makes it much easier for a sociopath to be camouflaged in our culture.

The ultimate manipulation is to kill someone, and sociopathy is murderous in a psychological sense - there's a kind of soul-murder going on.

The most reliable sign, the most universal behavior of unscrupulous people is not directed, as one might imagine, at our fearfulness. It is, perversely, an appeal to our sympathy.