I recall a lecture by John Glenn, the first American to go into orbit. When asked what went through his mind while he was crouched in the rocket nose-cone, awaiting blast-off, he replied, "I was thinking that the rocket has 20,000 components, and each was made by the lowest bidder."

It's becoming clear that in a sense the cosmos provides the only laboratory where sufficiently extreme conditions are ever achieved to test new ideas on particle physics. The energies in the Big Bang were far higher than we can ever achieve on Earth. So by looking at evidence for the Big Bang, and by studying things like neutron stars, we are in effect learning something about fundamental physics.

Crucial to science education is hands-on involvement: showing, not just telling; real experiments and field trips and not just "virtual reality".

Once the threshold is crossed when there is a self-sustaining level of life in space, then life's long-range future will be secure irrespective of any of the risks on Earth. Will this happen before our technological civilization disintegrates, leaving this as a might-have-been? Will the self-sustaining space communities be established before a catastrophe sets back the prospect of any such enterprise, perhaps foreclosing it forever? We live at what could be a defining moment for the cosmos.

In our interconnected world, novel technology could empower just one fanatic, or some weirdo with a mindset of those who now design computer viruses, to trigger some kind of disaster. Indeed, catastrophe could arise simply from technical misadventure - error rather than terror.

I think a few hundred years from now we'll start having the 'posthuman' era of different species.

It's better to read first rate science fiction than second rate science-it's a lot more fun, and no more likely to be wrong.