With crystals we are in a situation similar to an attempt to investigate an optical grating merely from the spectra it produces... But a knowledge of the positions and intensities of the spectra does not suffice for the determination of the structure. The phases with which the diffracted waves vibrate relative to one another enter in an essential way. To determine a crystal structure on the atomic scale, one must know the phase differences between the different interference spots on the photographic plate, and this task may certainly prove to be rather difficult.
Max von LaueFor in 1900 all electromagnetic radiation of longer wavelengths was already known at least to the extent that one could not seek in it the more striking characteristics of X-rays such as, for example, the strong penetrating power.
Max von Laue