I say to myself, 'I don't know how to act - and why does anybody want to look at me on-screen anymore?' ... Lots of actors feel that way. What gives you strength is also your weakness - your raging insecurity.

The work itself is the reward, and if I choose challenging work, it'll pay me back with interest. At least I'll be interested, even if nobody else is.

The career I chose was a drama major in college, at Yale, when I played a 90-year-old woman. One of my most celebrated roles. Then I played a really fat person. I played a lot of different things. That's how I thought I loved to wrangle my talent, my need to express myself. I like to do it that way.

I feel very strongly that we make decisions about what we're giving to the world, what we're withholding from the world, by virtue of what we put on our bodies.

I would like Martin Scorsese to be interested in a female character once in a while, but I don’t know if I’ll live that long.

Well my favorite is really really sharp, extra sharp, aged cheddar cheese.

Listening is everything. Listening is the whole deal. That's what I think. And I mean that in terms of before you work, after you work, in between work, with your children, with your husband, with your friends, with your mother, with your father. It's everything. And it's where you learn everything.