I find as long as I acknowledge the truth of something, then that's it. I know what it is and then I can operate. But if I overestimate the downside of something or the challenge of something and I get too obsessed about the difficulty of it, then I don't leave enough room to be open to the upside, the possibility.

The more I expect, the more unhappy I am going to be. The more I accept, the more serene I am.

When you're a short actor you stand on apple boxes, you walk on a ramp. When you're a short star everybody else walks in a ditch.

The 'Rescue Me' gig was a unique opportunity to play a character - a misanthropic, angry guy - who was so contrary to how people think of me.

You suffer the blow, but you capitalize on the opportunity left in its wake.

No, I got a GED in my 30s. My kids know that I never stop learning, and they know I love reading. I have books overflowing everywhere. I am current on today's events and I read the paper every day, and we talk about it, so they see that appetite.

It is ironic that in the same year we celebrate the 50th anniversary of the discovery of DNA, some would have us ban certain forms of DNA medical research. Restricting medical research has very real human consequences, measured in loss of life and tremendous suffering for patients and their families.