There's no substitute for rolling up your sleeves and working with the people who can make a difference. They get the benefit of your participation and you gain a direct understanding of the real problems and potential solutions, which makes you a more informed giver.

Earlier in this century, philanthropy often flowed from the wills of dead industrialists. In recent decades, it's as likely to have come from a very alive business leader, entertainer, artist or sports star. The most effective of these patrons begin the process of giving by asking what they care about passionately.

In financing growing companies, we always looked for human value that didn't appear on the balance sheet.

You've got to treat people as equals, and make them feel like it's their company. I don't know if I've had any impact or helped persuade Frank [to sell Eastern]. But, I can tell you, there were many discussions on the subject.

The rest of the world is growing so quickly, they'll be looking for anything to buy.

Dedicated researchers seek better treatments and cures for diabetes, kidney disease, Alzheimer's and every form of cancer. But these scientists face an array of disincentives. We can do better.

There's no substitute for rolling up your sleeves and working with the people who can make a difference. They get the benefit of your participation and you gain a direct understanding of the real problems and potential solutions, which makes you a more informed giver.