Growing up in India, I knew all I needed to change the world was one good opportunity, and I prepared myself for it. When that opportunity came - in the form of the chance to earn an engineering degree - I was ready.

Trust your gut instinct over spreadsheets. There are too many variables in the real world that you simply can't put into a spreadsheet. Spreadsheets spit out results from your inexact assumptions and give you a false sense of security. In most cases, your heart and gut are still your best guide.

Athletes at all ages are bigger and stronger than ever before. And they are being encouraged - sometimes even incentivized, as we recently learned was the case on at least one National Football League team - to play to injure.

I believe that entrepreneurs play an unmatched role and the accelerating pace of innovation is transforming the face of global challenges. You must think about the solution differently when you're trying to impact 1 billion people rather than affecting 1 million people.

The U.S. has spent billions of dollars on educating and supporting teachers or developing curricula but no resources are applied to 'improving the brain' that a student brings to the classroom.

Today, people idolize athletes and celebrities - and yes, highly successful and visionary business people like Bill Gates or Steve Jobs, but not the innovators who perhaps have not seen such high-flying levels of success. Can anyone name the inventors of GPS, which has such a huge impact on our lives today?

The human brain works as a binary computer and can only analyze the exact information-based zeros and ones (or black and white). Our heart is more like a chemical computer that uses fuzzy logic to analyze information that can't be easily defined in zeros and ones.