Just as an informal, nonscientific observation, most people's personalities don't seem to change very much during their lives. There are exceptions in the case of people who go through hugely traumatic events or suffer from brain injury or disease. Some would argue that religious conversions can have deep personality-altering effects. But these are all exceptions to the rule.
Neal StephensonOne of the most frightening things about your true nerd, for may people, is not that he's socially inept - because everybody's been there - but rather his complete lack of embarrassment about it.
Neal StephensonThe only thing that can effect a big change in personality is something that physically rewires the brain and/or alters the body's chemical milieu.
Neal StephensonI don't even want you to nod, that's how much you annoy me. Just freeze and shut up.
Neal StephensonEarly on, I settled on the first-person strategy as a way to deal with exposition and world-description issues. As long as the book is, it could have been far longer had I gone with an omniscient third-person narrator, or multiple point-of-view characters, since either of those would have enabled me to impart much more detailed information about the history and geography of the world.
Neal Stephenson