Anyone who has wrestled knows that it's the hardest thing in the world to do. Anyone who says something else is the hardest thing has never wrestled. That's what I have found. ... You don't wrestle because it's easy, you wrestle because it's hard. I don't do astrophysics because it's easy, I do it because it's hard. And I juxtapose the two in my mind, body, and soul all the time.

We hunger for significance, for signs that our personal existence is of special meaning to the universe. To that end, we’re all too eager to deceive ourselves and others, to discern a sacred image in a grilled cheese sandwich or find a divine warning in a comet

They all knew the mothership was coming, they all knew it was a flying saucer, they all knew it came from another planet through the vacuum of space. And so what do they do, to the left of that monument? They set up runway lights. And I'm thinking, if you could travel through the vacuum of space, you don't need runway lights. Runway lights are if you're using air for lift. Aliens would not need air for lift.

The universe is hilarious! Like, Venus is 900 degrees. I could tell you it melts lead. But that's not as fun as saying, 'You can cook a pizza on the windowsill in nine seconds.' And next time my fans eat pizza, they're thinking of Venus!

The Big Bang Theory: When geeky scientists can be main characters in a hit prime time series, you know there's hope for the world.

One thing in life is for certain, the more profoundly baffled you have been in your life, the more open your mind becomes to new ideas.

A conspiracy theorist is a person who tacitly admits that they have insufficient data to prove their points. A conspiracy is a battle cry of a person with insufficient data.