FM signals and those of broadcast television...travel out to space at the speed of light. Any eavesdropping alien civilization will know all about our TV programs (probably a bad thing), will hear all our FM music (probably a good thing), and know nothing of the politics of AM talk-show hosts (probably a safe thing).

If an alien lands on your front lawn and extends an appendage as a gesture of greeting, before you get friendly, toss it an eightball. If the appendage explodes, then the alien was probably made of antimatter. If not, then you can proceed to take it to your leader.

... informed ignorance provides the natural state of mind for research scientists at the ever-shifting frontiers of knowledge. People who believe themselves ignorant of nothing have neither looked for, nor stumbled upon, the boundary between what is known and unknown in the cosmos.

I have a very high respect for professional comedians. What they do astonishes me. You have to be really smart and absorb everything, repackage it, bring it back to the person, and make them laugh at themselves. I can make people laugh during my talks because they didn't come to have me make them laugh. It's added value. So my job is way easier than that of a professional comic.

We hunger for significance, for signs that our personal existence is of special meaning to the universe. To that end, we’re all too eager to deceive ourselves and others, to discern a sacred image in a grilled cheese sandwich or find a divine warning in a comet

God is an ever-receding pocket of scientific ignorance that's getting smaller and smaller and smaller as time moves on.

What's up with chicks and science?