If humans one day become extinct from a catastrophic collision, there would be no greater tragedy in the history of life in the universe. Not because we lacked the brain power to protect ourselves but because we lacked the foresight. The dominant species that replaces us in post-apocalyptic Earth just might wonder, as they gaze upon our mounted skeletons in their natural history museums, why large headed Homo sapiens fared no better than the proverbially peabrained dinosaurs.

Lots of people think, well, we're humans; we're the most intelligent and accomplished species; we're in charge. Bacteria may have a different outlook: more bacteria live and work in one linear centimeter of your lower colon than all the humans who have ever lived. That's what's going on in your digestive tract right now. Are we in charge, or are we simply hosts for bacteria? It all depends on your outlook.

If an alien lands on your front lawn and extends an appendage as a gesture of greeting, before you get friendly, toss it an eightball. If the appendage explodes, then the alien was probably made of antimatter. If not, then you can proceed to take it to your leader.

We are all connected to each other biologically, to the earth chemically and to the rest of the universe atomically. That's kinda cool! That makes me smile and I actually feel quite large at the end of that. It's not that we are better than the universe, we are part of the universe. We are in the universe and the universe is in us.

For me, one of the most fertile consequences of the space program is the extent to which it stimulates people to innovate because they want to create a different tomorrow than what they're living in today. And it's that culture of innovation that spawns entirely new economies.

Everything we do, every thought we've ever had, is produced by the human brain. But exactly how it operates remains one of the biggest unsolved mysteries, and it seems the more we probe its secrets, the more surprises we find.

Here's what I'm wondering: if, digitally, you can remove red-eye, smooth over wrinkles, make people look thinner, then why don't we have the technology to make me sing better?