The cognitive functioning of a human brain depends on a delicate orchestration of many factors, especially during the critical stages of embryo development-and it is much more likely that this self-organizing structure, to be enhanced, needs to be carefully balanced, tuned, and cultivated rather than simply flooded with some extraneous potion.

We should not be confident in our ability to keep a super-intelligent genie locked up in its bottle forever.

Had Mother Nature been a real parent, she would have been in jail for child abuse and murder.

Our approach to existential risks cannot be one of trial-and-error. There is no opportunity to learn from errors. The reactive approach - see what happens, limit damages, and learn from experience - is unworkable. Rather, we must take a proactive approach. This requires foresight to anticipate new types of threats and a willingness to take decisive preventive action and to bear the costs (moral and economic) of such actions.

For healthy adult people, the really big thing we can foresee are ways of intervening in the ageing process, either by slowing or reversing it.

There are some problems that technology can't solve.

The challenge presented by the prospect of superintelligence, and how we might best respond is quite possibly the most important and most daunting challenge humanity has ever faced. And-whether we succeed or fail-it is probably the last challenge we will ever face.