When at last I came upon the right book, the feeling was violent: it blew open a hole in me that made life more dangerous because I couldn't control what came through it.

The fact that you got a little happier today doesn't change the fact that you also became a little sadder. Every day you become a little more of both, which means that right now, at this exact moment, you're the happiest and saddest you've ever been in your whole life.

Now that mine is almost over, I can say that the one thing that struck me most about life is the capacity for change. One day you're a person and the next day they tell you you're a dog. At first it's hard to bear, but after a while you learn not to look at it as a loss. There's even a moment when it becomes exhilarating to realize just how little needs to stay the same for you to continue the effort they call, for lack of a better word, being human.

Alone in my room, wrapped in a blanket, I whimpered and talked aloud to myself, recalling the lost glory of my youth when I considered myself, and was considered by others, a bright and capable person. It seemed that was all gone now.

Sometimes just to paint a head you have to give up the whole figure. To paint a leaf, you have to sacrifice the whole landscape. It might seem like you're limiting yourself at first, but after a while you realize that having a quarter of an inch of something you have a better chance of holding on to a certain feeling of the universe than if you pretended to be doing the whole sky.

Holding hands, for example, is a way to remember how it feels to say nothing together.

He spoke of human solitude, about the intrinsic loneliness of a sophisticated mind, one that is capable of reason and poetry but which grasps at straws when it comes to understanding another, a mind aware of the impossibility of absolute understanding. The difficulty of having a mind that understands that it will always be misunderstood.