I grew up in the Baptist Church, and going to church with my father; I remember being 8 years old, trying to determine whether I was really ready to give up sin, and for days I agonized.

There's nobody who would be willing to do an interview on a regular basis that you can't go and Google and find out what has happened to them in the past week. There's nobody.

Wherever you are, that’s your stage, your circle of influence. That’s your talk show, that’s where your power lies. ... You have the power to change somebody’s life. Everyone has a calling, and your real job in life is to figure out what that is and get about the business of doing it.

I've talked to nearly 30,000, people on this show, and all 30,000, had one thing in common: They all wanted validation...I would tell you that every single person you will ever meet shares that common desire.

To kick things off, [television show host Andy Cohen] asked the last time Winfrey had smoked marijuana. 'Uh ... 1982,' Winfrey replied. 'Let's hang out after the show,' Cohen joked. 'Okay,' Winfrey laughed. 'I hear it's gotten better.'

A gift isn't a gift unless it has meaning. Just giving things to people, especially children, create the expectation of more things.

You become what you believe. And to believe that you are created by the power that's greater than yourself means anything is possible.