If biking is your passion, set aside time to enjoy a good ride.

Now I'm just known as McDreamy, I've lost all identity as Patrick Dempsey, I'm now McDreamy.

Fame is fleeting. Sometimes people like you, sometimes they don’t. Not all people are going to like you.

My big thing is to make sure the lipsticks taste good when you kiss. And, well, so far they taste pretty darn good.

I did a play called 'On Golden Pond' in a dinner theater in Maine and then went to New York for a talent competition having put together a three-man juggling routine and some one-liners and I got myself an agent from that

I think dreams can come true, but not necessarily like fairy-tales. It's not always so perfect like that.

When you discover first love as a teenager, your whole life revolves around it and you open yourself up to it.