By 2020 the U.S. will be short 91,000 doctors. There's no way we can educate enough doctors to make up that shortfall, and other countries are far worse off.

During the next 50 years, in countless cycles, in countless entrepreneurial companies, this let's just go and do it mentality will help us finally get off the planet and irreversibly open the space frontier. The capital and tools are finally being placed into the hands of those willing to risk, willing to fail, willing to follow the dreams.

Super-ambitious goals tend to be unifying and energizing to people; but only if they believe there's a chance of success.

More than ever before in history, individuals can now band together to solve grand challenges. We face enormous problems, but we 'as individuals' have enormous power to solve them.

We live in a world bathed in 5,000 times more energy than we consume as a species in the year, in the form of solar energy.

The first trillionaire can be made in space.

What opened up the American West was the fact that you owned the real estate. You owned the gold mines, the oil wells. The creation of these, back then, million dollar industries drove the railroads and eventually the airlines to provide this kind of transportation.