By 2020 the U.S. will be short 91,000 doctors. There's no way we can educate enough doctors to make up that shortfall, and other countries are far worse off.

Eight billion people will have Internet access by 2020.

Every second of every day, our senses bring in way too much data than we can possibly process in our brains.

Today, philanthropy is a very unsophisticated, old world process where people who make a shitload of money go and give it away and when they're making their money, they're focused on 10x, 100x returns on the dollar.

More than ever before in history, individuals can now band together to solve grand challenges. We face enormous problems, but we 'as individuals' have enormous power to solve them.

You need to be a little crazy to change the world, and you can’t really fake it.

In 1980, during my sophomore year at MIT, I realized that the school didn't have a student space organization. I made posters for a group I called Students for the Exploration and Development of Space and put them up all over campus. Thirty-five people showed up. It was the first thing I ever organized, and it took off!