It was fun shooting with Josh [Holloway], not just how great he is, but just how handsome he is.

I certainly have played a lot of strong characters, and I love playing a strong character.

If you do an episode about something like transverse myelitis, it's a real disease that's out there, there are a lot of people that have it, and it's hard to get funding for them because people don't know about it. There are actually a lot of doctors that don't know about it. But if you do an episode of House, all of a sudden 15 million people are hearing the words, and it's an opportunity.

I know I'm going to sound like an idiot, because I actually think that everybody's the nicest guy ever, but I'm telling you: George Clooney, Roland Emmerich, Sidney Lumet - these are literally the nicest people.

I was a greasy short-order cook. I just liked being greasy! That was a real departure for me.

I guess actors don't like to direct each other.

I always enjoy being the obvious homunculus of the pair.