An experiment not worth doing is not worth doing well.

The art of research [is] the art of making difficult problems soluble by devising means of getting at them.

It is a truism to say that a good experiment is precisely that which spares us the exertion of thinking: the better it is, the less we have to worry about its interpretation, about what it really means.

The case I shall find evidence for is that when literature arrives, it expels science.

Innocent, unbiased observation is a myth.

It is a common failing-and one that I have myself suffered from-to fall in love with a hypothesis and to be unwilling to take no for an answer. A love affair with a pet hypothesis can waste years of precious time. There is very often no finally decisive yes, though quite often there can be a decisive no.

It is the great glory as well as the great threat of science that everything which is in principle possible can be done if the intention to do it is sufficiently resolute.