It is a truism to say that a good experiment is precisely that which spares us the exertion of thinking: the better it is, the less we have to worry about its interpretation, about what it really means.

Scientists are people of very dissimilar temperaments doing different things in very different ways. Among scientists are collectors, classifiers and compulsive tidiers-up; many are detectives by temperament and many are explorers; some are artists and others artisans. There are poet-scientists and philosopher-scientists and even a few mystics.

[A certain class of explanations in science are] analgesics that dull the ache of incomprehension without removing the cause.

It is the great glory as well as the great threat of science that everything which is in principle possible can be done if the intention to do it is sufficiently resolute.

I shall borrow two words used for a slightly different purpose by the great demographer Alfred Lotka to distinguish between the two systems of heredity enjoyed by man: endosomatic or internal heredity for the ordinary or genetical heredity we have in common with animals; and exosomatic or external heredity for the non-genetic heredity that is peculiarly our own - the heredity that is mediated through tradition, by which I mean the transfer of information through non-genetic channels from one generation to the next.

Ask a scientist what he conceives the scientific method to be and he will adopt an expression that is at once solemn and shifty-eyed: solemn, because he feels he ought to declare an opinion; shifty-eyed, because he is wondering how to conceal the fact that he has no opinion to declare.

No scientist is admired for failing in the attempt to solve problems that lie beyond his competence. ... Good scientists study the most important problems they think they can solve. It is, after all, their professional business to solve problems, not merely to grapple with them.