A lot can be said for the infinite mercies of God, but the smarts of a good pharmacist, when you get down to it, is worth more.

The mentally disturbed do not employ the Principle of Scientific Parsimony: the most simple theory to explain a given set of facts. They shoot for the baroque.

I love you,' Rachael said. 'If I entered a room and found a sofa covered with your hide I'd score very high on the Voigt-Kampff test.

You have to be with other people, he thought. In order to live at all. I mean before they came here I could stand it... But now it has changed. You can't go back, he thought. You can't go from people to nonpeople." - J.R. Isidore

You will be required to do wrong no matter where you go. It is the basic condition of life, to be required to violate your own identity. At some time, every creature which lives must do so. It is the ultimate shadow, the defeat of creation; this is the curse at work, the curse that feeds on all life. Everywhere in the universe.

What they do not comprehend is man's helplessness. I am weak, small, of no consequence to the universe. It does not notice me; I live on unseen. But why is that bad? Isn't it that way? Whom the gods notice they destroy. Be small... and you will escape the jealousy of the great.

Grief causes you to leave yourself. You step outside your narrow little pelt. And you can’t feel grief unless you’ve had love before it - grief is the final outcome of love, because it’s love lost. […] It’s the cycle of love completed: to love, to lose, to feel grief, to leave, and then to love again. Grief is the awareness that you will have to be alone, and there is nothing beyond that because being alone is the ultimate final destiny of each individual living creature. That’s what death is, the great loneliness.