Machines will follow a path that mirrors the evolution of humans. Ultimately, however, self-aware, self-improving machines will evolve beyond humans' ability to control or even understand them.

The profound aspect of technology is that once secrets are revealed, the magic doesn't disappear.

As you go out to the 2040s, now the bulk of our thinking is out in the cloud. The biological portion of our brain didn't go away but the nonbiological portion will be much more powerful. And it will be uploaded automatically the way we back up everything now that's digital.

To transcend means to "go beyond," but this need not compel us to an ornate dualist view that regards transcendent levels of reality (e.g., the spiritual level) to be not of this world. We can "go beyond" the "ordinary" powers of the material world through the power of patterns. Rather than a materialist, I would prefer to consider myself a "patternist." It's through the emergent powers of the pattern that we transcend.

The story of evolution unfolds with increasing levels of abstraction.

I do have to pick my priorities. Nobody can do everything.

We have the means right now to live long enough to live forever. Existing knowledge can be aggressively applied to dramatically slow down aging processes so we can still be in vital health when the more radical life-extending therapies from biotechnology and nanotechnology become available. But most baby boomers won't make it because they are unaware of the accelerating aging process in their bodies and the opportunity to intervene.