Some years ago I was struck by the large number of falsehoods that I had accepted as true in my childhood, and by the highly doubtful nature of the whole edifice that I had subsequently based on them. I realized that it was necessary, once in the course of my life, to demolish everything completely and start again right from the foundations if I wanted to establish anything at all in the sciences that was stable and likely to last.

So blind is the curiosity by which mortals are possessed, that they often conduct their minds along unexplored routes, having no reason to hope for success, but merely being willing to risk the experiment of finding whether the truth they seek lies there.

I am indeed amazed when I consider how weak my mind is and how prone to error.

Reason is nothing without imagination.

Even the mind depends so much on temperament and the disposition of one's bodily organs that, if it is possible to find a way to make people generally more wise and more skilful than they have been in the past, I believe that we should look for it in medicine. It is true that medicine as it is currently practiced contains little of much use.

The principal effect of the passions is that they incite and persuade the mind to will the events for which they prepared the body.

Sensations are nothing but confused modes of thinking.