The increase in the greenhouse gas concentrations in the atmosphere are having an effect. Our ability to predict that effect is very limited.

We are making tremendous progress that ISIS really does present to the homeland and to other homelands of allies around the world.

I've made my own comments as to our vales as well in a speech I gave to the State Department.

I think continued actions by Bashar al-Assad clearly call into any question of him expecting to have any legitimacy to continue as the leader of Syria. With each of those actions, like attack with conventional weapons, barrel bombs and block humanitarian aid he really undermines his own legitimacy.

Russia and the USA are two largest nuclear powers in the world; it's a really important relationship. How do we start making this work? How do we live with one another? How do we work with one another? We simply have to find a way to go forward.

We've seen what violent regime change looks like in Libya and the kind of chaos that can be unleashed. And, indeed, the kind of misery that it enacts on its own people.

I don't believe anyone doubts the American people's values or the commitment of the American government or the government's agencies to advancing those values and defending those values.