An ecosystem, you can always intervene and change something in it, but there's no way of knowing what all the downstream effects will be or how it might affect the environment. We have such a miserably poor understanding of how the organism develops from its DNA that I would be surprised if we don't get one rude shock after another.

With respect to phenomena like mass extinction, somebody might say why worry about it because in a geological perspective mass extinctions aren't so bad, they wipe out some things and then 10 million years down the road we get new and interesting objects.But I tell you mass extinctions are really awful for folks caught in the midst of them.

History has got a lot to do with unique circumstances under certain particular cases and grand theories will always find counter cases. I don't think that people whose expertise lies in one thing should try to make grand theories about something (a) where it's very hard to get the evidence to prove that you're right and (b) where it's much too easy to make up stories that seem right.

People who have various kinds of politics for whom it is congenial for their apriority politics to say yes, things are getting much worse. They are opposed by people who also have a priori politics saying that this is the best of all possible worlds, capitalism is the greatest thing since sliced bread and you're just alarmists and so on and they can massage the data so it fits them.

We take the side of science in spite of the patent absurdity of some of its constructs, in spite of its failure to fulfill many of its extravagant promises of health and life, in spite of the tolerance of the scientific community for unsubstantiated just-so stories, because we have a prior commitment, a commitment to materialism... We cannot allow a Divine Foot in the door.

We do have tendency, now in biology especially to make up stories, to make theoretical biology a kind of game, in fact we have game theory in biology which is meant to use the theory of games to make predictions or explain things.

In my mind the job of a natural scientist is to bend over backwards to say something which can be demonstrated to be true or at least which is not of such a nature that there's no way to demonstrate that it's false.