There is no harm in doubt and skepticism, for it is through these that new discoveries are made.

There in wine is found the great generalization: all life is fermentation.

But there is nothing in biology yet found that indicates the inevitability of death.

The game I play is a very interesting one. It's imagination in a straightjacket, which is this: that it has to agree with the known laws of physics. ... It requires imagination to think of what's possible, and then it requires an analysis back, checking to see whether it fits, whether its allowed, according to what's known, okay?

You see, I get such fun out of thinking that I don't want to destroy this most pleasant machine that makes life such a big kick.

In its efforts to learn as much as possible about nature, modern physics has found that certain things can never be "known" with certainty. Much of our knowledge must always remain uncertain. The most we can know is in terms of probabilities.

So, ultimately, in order to understand nature it may be necessary to have a deeper understanding of mathematical relationships. But the real reason is that the subject is enjoyable, and although we humans cut nature up in different ways, and we have different courses in different departments, such compartmentaliz ation is really artificial, and we should take our intellectual pleasures where we find them.