A poet once said, "The whole universe is in a glass of wine." We will probably never know in what sense he meant that, for poets do not write to be understood. But it is true that if we look at a glass of wine closely enough we see the entire universe.

I have the advantage of having found out how hard it is to get to really know something. How careful you have to be about checking your experiments. How easy it is to make mistakes and fool yourself. I know what it means to know something.

It is going to be necessary that everything that happens in a finite volume of space and time would have to be analyzable with a finite number of logical operations. The present theory of physics is not that way, apparently. It allows space to go down into infinitesimal distances, wavelengths to get infinitely great, terms to be summed in infinite order, and so forth; and therefore, if this proposition [that physics is computer-simulatable] is right, physical law is wrong.

There is nothing in biology yet found that indicates the inevitability of death. This suggests to me that it is not at all inevitable and that it is only a matter of time before biologists discover what it is that is causing us the trouble.

The inside of a computer is as dumb as hell but it goes like mad!

Physics is not the most important thing. Love is.

When a scientist doesn't know the answer to a problem, he is ignorant. When he has a hunch as to what the result is, he is uncertain. And when he is pretty darn sure of what the result is going to be, he is still in some doubt. We have found it of paramount importance that in order to progress we must recognize our ignorance and leave room for doubt. Scientific knowledge is a body of statements of varying degrees of certainty - some most unsure, some nearly sure, but none absolutely certain.