First you guess. Don't laugh, this is the most important step. Then you compute the consequences. Compare the consequences to experience. If it disagrees with experience, the guess is wrong. In that simple statement is the key to science. It doesn't matter how beautiful your guess is or how smart you are or what your name is. If it disagrees with experience, it's wrong. That's all there is to it.
Richard P. FeynmanThis attitude of mind - this attitude of uncertainty - is vital to the scientist, and it is this attitude of mind which the student must first acquire. It becomes a habit of thought. Once acquired, we cannot retreat from it anymore.
Richard P. FeynmanIn fact the total amount that a physicist knows is very little. He has only to remember the rules to get him from one place to another and he is all right.
Richard P. Feynman