First you guess. Don't laugh, this is the most important step. Then you compute the consequences. Compare the consequences to experience. If it disagrees with experience, the guess is wrong. In that simple statement is the key to science. It doesn't matter how beautiful your guess is or how smart you are or what your name is. If it disagrees with experience, it's wrong. That's all there is to it.

Ordinarily it would take me about fifteen minutes to get a hallucination going," wrote Feynman, "but on a few occasions, when I smoked some marijuana beforehand, it came very quickly.

What would happen if we could arrange the atoms one by one the way we want them?

It is not unscientific to make a guess, although many people who are not in science think it is.

If you don't like it, go somewhere else, to another universe where the rules are simpler.

During the Middle Ages there were all kinds of crazy ideas, such as that a piece of rhinoceros horn would increase potency. Then a method was discovered for separating the ideas - which was to try one to see if it worked, and if it didn't work, to eliminate it. This method became organized, of course, into science.

When a scientist doesn't know the answer to a problem, he is ignorant. When he has a hunch as to what the result is, he is uncertain. And when he is pretty darn sure of what the result is going to be, he is still in some doubt. We have found it of paramount importance that in order to progress we must recognize our ignorance and leave room for doubt. Scientific knowledge is a body of statements of varying degrees of certainty - some most unsure, some nearly sure, but none absolutely certain.