["John F. Kennedy" movie] was just really clever storytelling.

If people are watching me 365 days a year, 360 days they might be bored to tears. And on the other five days, maybe I would qualify as Satan.

All the shows we did pre-airdate, and I'd come out - "Rob Lowe!" - and it was [Offers bored applause.] After the show aired? I came out - "Rob Lowe!" - and the place was, like, bedlam. And then the next week, they wouldn't let anyone under the age of 20 into the audience. And I'm going, "So that's how it works! Okay!"

When I had my Comedy Central roast, David [Spade] was my first choice to be roastmaster, because I adore him. He's funny as hell, and nobody is meaner.

[Doctor Cukrowicz in Suddenly, Last Summer is] is one of the most unpronounceable roles in the modern-day theater day canon, and one of the most boring!

There's an argument that maybe [The Grinder] was better suited for streaming or cable. I don't know. I still like to think there's a place for smart, subversive, original comedies on networks.

The really good thing about my career is that I never went through a phase where I played characters who had names like "Partygoer," "Waiter," or "Guy #1."