Ignorance is the Mother of Devotion.

Out of too much learning become mad.

Good science is more than the mechanics of research and experimentation. Good science requires that scientists look inward-to contemplate the origin of their thoughts. The failures of science do not begin with flawed evidence or fumbled statistics; they begin with personal self-deception and an unjustified sense of knowing.

We want to be known for having original ideas, inspired hunches, and gut feelings that make a difference. Indeed, a "well-honed sixth sense"' is considered a measure of the good clinician. But being a good doctor also requires sticking with the best medical evidence, even if it contradicts your personal experience. We need to distinguish between gut feeling and testable knowledge, between hunches and empirically tested evidence.

Certainty and similar states of ‘knowing what we know’ arise out of involuntary brain mechanisms that, like love or anger, function independently of reason.

Properly conducted scientific studies . . . give us a pretty good idea of when something is likely to be correct. To me, pretty good is a linguistic statistic that falls somewhere in between more likely than not and beyond a reasonable doubt, et avoides the pitfalls arising from the belief in complete objectivity.

It is most true, stylus virum arguit, - our style betrays us.