The pure culture is the foundation for all research on infectious disease.

To prove that tuberculosis is caused by the invasion of bacilli, and that it is a parasitic disease primarily caused by the growth and multiplication of bacilli, it is necessary to isolate the bacilli from the body, to grow them in pure culture until they are freed from every disease product of the animal organism, and, by introducing isolated bacilli into animals, to reproduce the same morbid condition that is known to follow from inoculation with spontaneously developed tuberculous material.

From my numerous observations, I conclude that these tubercle bacilli occur in all tuberculous disorders, and that they are distinguishable from all other microorganisms.

If my efforts have led to greater success than usual, this is due, I believe, to the fact that during my wanderings in the field of medicine, I have strayed onto paths where the gold was still lying by the wayside. It takes a little luck to be able to distinguish gold from dross, but that is all.

The pure culture is the foundation for all research on infectious disease.

In view of the epidemiological situation in Germany, the lack of evidence for the effectiveness of the BCG-vaccine and the not uncommen severe, undesired side-effects of the BCG vaccine, the STIKO can no longer support the recommendation for this vaccination.

Our studies have shown that all cases of typhoid of this type have arisen by contact, that is, carried directly from one person to another. There was no trace of a connection to drinking water.