It's paradoxical that where people are the most closely crowded, in the big coastal cities in the East and West, the loneliness is the greatest... The explanation, I suppose, is that the physical distance between people has nothing to do with loneliness. It's psychic distance...

Science probes; it does not prove. Imagine Newton's reaction to an objector of his law of gravity who argued that he could not establish a universal law because he had not observed every falling apple, much less proved the law of gravity - there might, after all, be an apple that levitates! Why should a group of simple, stable compounds of carbon, hydrogen, oxygen and nitrogen struggle for billions of years to organize themselves into a professor of chemistry?

Quality... you know what it is, yet you don't know what it is.

Within a Metaphysics of Quality, science is a set of static intellectual patterns describing this reality, but the patterns are not the reality they describe.

Even in the presence of others he was completely alone.

Metaphysics is a restaurant where they give you a thirty thousand page menu, and no food.

Even though quality cannot be defined, you know what quality is.