Every cent that goes to research is changing the lives of patients and their families right now.

Since the day I finished shooting there's been at least one person come up to me every single day and then after the trailer came out, at least four. It's absolutely bizarre to me. This was before there was any systematic promotion of the movie. It's just completely nuts.

I don't think anyone can understand what's happening. Something like this is so rare. It's a mix of chance and coincidence. You wake up one day and you're suddenly a star.. Really weird. All of a sudden everyone knows who you are while you haven't changed one bit

I have very, very specific ideas about how I want to do my work and how I want to be perceived and to the point of ridiculousness sometimes.

Your ideas dry up sometimes, and you get lazy sometimes 'cause you're around the same people. That was the good thing about having different directors. You had to stay on your toes.

[A fan] said, 'What can I do to get your attention?' I was like 'Um, just take your clothes off.' She stood there and frantically started taking her clothes off and got dragged out of the room by security.

To be honest, everyone thinks that a digital camera is more reliable and every single time I work on any movie, it's just as many problems, the memory card doesn't work or blah blah blah, it overheats; it's the same volume as another camera. I think people are bit taken in by it.