I did not study science at school until I was 13, when I was totally turned on by a seemingly dreary old teacher who suddenly, unannounced, manufactured a huge explosion in the middle of a totally boring monologue. From then on, all of his class wanted to make explosions.

It's extraordinary to think that if you walked into a room and said you had never heard of Hamlet, you would be regarded as a Philistine. But you could walk into the same room and say, 'I don't know what a proton is,' and people would just laugh and say, 'Why should you know?'

We are more dependent on science and engineering than at any other time in history. However, there is plenty of evidence that far too many people are scientifically illiterate, often having been put off science at school.

I don't believe in regretting - one should try to move on. My mum was good at that. She was deeply in love with my father, and he died when I was nine. She remarried, and her second husband died, too. I saw the grieving process she went through. My mother had this way of moving on. It was a fine trait.

In prehistoric times, Homo sapiens was deeply endangered. Early humans were less fleet of foot, with fewer natural weapons and less well-honed senses than all the predators that threatened them. Moreover, they were hampered in their movements by the need to protect their uniquely immature young - juicy meals for any hungry beast.

Surgeons always underestimate the pain and disability involved in what they do to people.

It is important that legislation keeps pace with scientific progress.