... the actual and physical conduct of an experiment must govern the statistical procedure of its interpretation.

Experimental observations are only experience carefully planned in advance, and designed to form a secure basis of new knowledge.

Natural selection is a mechanism for generating an exceedingly high degree of improbability.

Modern statisticians are familiar with the notion that any finite body of data contains only a limited amount of information on any point under examination; that this limit is set by the nature of the data themselves, and cannot be increased by any amount of ingenuity expended in their statistical examination: that the statistician's task, in fact, is limited to the extraction of the whole of the available information on any particular issue.

The more highly adapted an organism becomes, the less adaptable it is to any new change.

No aphorism is more frequently repeated in connection with field trials, than that we must ask Nature few questions, or, ideally, one question, at a time. The writer is convinced that this view is wholly mistaken. Nature, he suggests, will best respond to a logical and carefully thought out questionnaire; indeed, if we ask her a single question, she will often refuse to answer until some other topic has been discussed.

We may consequently state the fundamental theorem of Natural Selection in the form: The rate of increase in fitness of any organism at any time is equal to its genetic variance in fitness at that time.