Anything from making a mistake on an experiment that would ruin some scientist on earth's experiment - career, potentially - to doing something wrong with the satellite that a country was depending on for its communications, to making some mistake that could actually cost you and the crew either a mission or your lives. So there is a lot of pressure that's put on every astronaut to just make sure that he or she understands exactly what to do, exactly when to do it, and is trained and prepared to carry it out.
Sally RideThe most important steps that I followed were studying math and science in school. I was always interested in physics and astronomy and chemistry and I continued to study those subjects through high school and college on into graduate school. That's what prepared me for being an astronaut; it actually gave me the qualifications to be selected to be an astronaut.
Sally Ride