Mysticism is a rational enterprise. Religion is not. The mystic has recognized something about the nature of consciousness prior to thought, and this recognition is susceptible to rational discussion. The mystic has reasons for what he believes, and these reasons are empirical. The roiling mystery of the world can be analyzed with concepts (this is science), or it can be experienced free of concepts (this is myticism). Religion is nothing more than bad concepts held in place of good ones for all time. It is the denial-at once full of hope and full of fear-of the vastitude of human ignorance.

We are now in the 21st century: all books, including the Koran, should be fair game for flushing down the toilet without fear of violent reprisal.

The only thing that permits human beings to collaborate with one another in a truly open-ended way is their willingness to have their beliefs modified by new facts. Only openness to evidence and argument will secure a common world for us.

The power of psychedelics... is that they often reveal, in the span of a few hours, depths of awe and understanding that can otherwise elude us for a lifetime.

While believing strongly, without evidence, is considered a mark of madness or stupidity in any other area of our lives, faith in God still holds immense prestige in our society. Religion is the one area of our discourse where it is considered noble to pretend to be certain about things no human being could possibly be certain about. It is telling that this aura of nobility extends only to those faiths that still have many subscribers. Anyone caught worshipping Poseidon, even at sea, will be thought insane.

All I'm arguing for really is that we should have a conversation where the best ideas really thrive, where there's no taboo against criticizing bad ideas, and where everyone who shows up, in order to get their ideas entertained, has to meet some obvious burdens of intellectual rigor and self-criticism and honesty-and when people fail to do that, we are free to stop listening to them. What religion has had up until this moment is a different set of rules that apply only to it, which is you have to respect my religious certainty even though I'm telling you I arrived at it irrationally.

Hope is easy; knowledge is hard. Science is the one domain in which we human beings make a truly heroic effort to counter our innate biases and wishful thinking. Science is the one endeavor in which we have developed a refined methodology for separating what a person hopes is true from what he has good reason to believe.