While the Environmental Genome Project does not seek to assign allele frequencies, we are aware of the importance of accurate allele frequency estimates for future epidemiologic studies and the large sample sizes such estimates will require.

We all recognize that in recent decades, many important achievements have helped create a cleaner, healthier environment, yet our national needs in environmental health are not being fully met.

The liquid state of modernity is corrosive to continuity.

As population susceptibilities are better understood, we will be in a better position than we are in today to make informed decisions about risk management.

Compulsive modernization is the insatiable desire to change and grow.

It is important to consider whether the sample size selected by the Environmental Genome Project will provide sufficient power to discover most alleles relevant to gene-environment interactions.

One of the biggest challenges to medicine is the incorporation of information technology in our practices.